G h o s t l y.

New research from the University of Leicester (UK) concludes that lifestyle is associated with longer life expectancy also in the case of people with multiple chronic diseases. A new research from the University of Leicester (United Kingdom) with a pioneering character, concludes that lifestyle is associated with a longer life expectancy also in the case of people with multiple chronic diseases. And it is that to date there was no study that would quantify whether the risk of death associated with individual and combined risk factors depends on the presence of multiple chronic conditions. And the results of the research, led by Yogini Chudasama and published in the journal 'PLOS Medicine', indicates that a very healthy lifestyle, even with the existence of chronic pathologies, is associated with up to 6.3 more years of life for for men and 7.6 years for women after analyzing data collected between 2006 and 2010 from 480,940 adults between 38 and 73 years old from the UK Biobank, whose follow-up was extended until 2016. The finding can be considered very relevant when we consider that the number of people with two or more long-term physical or mental health conditions is increasing rapidly around the world, and they have worse health outcomes and an increased risk of mortality due to What acting on a modifiable risk factor such as lifestyle can be decisive, although it should be noted that the study is observational and causality cannot be established.

It was on September 23, 1935 when the first corporate offices of General Motors de México were inaugurated. Under the direction of Mr. Ivan C. Dresser, they settled on the second floor of Casa Colonia on Calle de Uruguay, on the corner of Avenida 20 de Noviembre, in the Historic Center of Mexico City. With only 36 employees, General Motors de México S.A. was legally established. The following year, on April 16, 1936, the first stone of its future offices was laid. However, the American corporation already had a presence in our country since years before, in 1921, General Motors decided to introduce the Buick brand; By 1923, seven distributors had been established in the national territory. By the 1930s, the rapid growth of the Mexican economy, the increase in agricultural activities and the government's interest in promoting industry and the construction of roads, drove the demand for motorized vehicles. In 1937, President Lázaro Cárdenas inaugurated GM's first plant, which has contributed to the production of just over 15 million vehicles and almost 30 million engines in the company's four complexes. This plant initially had 222 workers and an area of 9,308 square meters. The production of trucks had, in the beginning, a speed of 10 units per day. Photo: Courtesy General Motors It was on September 23, 1935 when the first corporate offices of General Motors de México were inaugurated. Under the direction of Mr. Ivan C. Dresser, they settled on the second floor of Casa Colonia on Calle de Uruguay, on the corner of Avenida 20 de Noviembre, in the Historic Center of Mexico City. With only 36 employees, General Motors de México S.A. was legally established. The following year, on April 16, 1936, the first stone of its future offices was laid. However, the American corporation already had a presence in our country since years before, in 1921, General Motors decided to introduce the Buick brand; By 1923, seven distributors had been established in the national territory. By the 1930s, the rapid growth of the Mexican economy, the increase in agricultural activities and the government's interest in promoting industry and the construction of roads, drove the demand for motorized vehicles. In 1937, President Lázaro Cárdenas inaugurated GM's first plant, which has contributed to the production of just over 15 million vehicles and almost 30 million engines in the company's four complexes. This plant initially had 222 workers and an area of 9,308 square meters. The production of trucks had, in the beginning, a speed of 10 units per day. This plant was followed by the Technical Training Center at the Mexico City plant in 1954, by 1963 the construction of the GM Toluca Complex, which began operations in 1965. In this facility, an Engines plant and a Foundry plant were built to fulfill with the then National Integration Plan of the Automotive Industry that decreed that 60% of the components of the units had to be produced locally. In this same place and in April of this year, the production of N1 and N95 masks was implemented to support the fight against the Covid-19 pandemic. The rest of the installations arrived in the following years. For example, the Ramos Arizpe complex, where models such as the Chevrolet Citation, Century or Chevy have been produced, opened its doors in 1981 while in 1995 the Silao Complex started operations; today Cheyenne, Silverado and Sierra pickups are produced there. That same year the Regional Engineering Center was established in Touca, in 1996 the After-Sales Service Center was inaugurated in Toluca. In 2008 the San Luis Potosí Complex began operations after a construction period of just 14 months.

Recent observations of galaxy clusters reveal a discrepancy with the dark matter hypothesis, leading to a resurgence of debate about the actual existence of this elusive ingredient in the universe. DARK MATTER IN CRISIS Most of us astronomers tend to speak of dark matter as if it were an ingredient of the universe of unknown nature, formed by some type of exotic particles yet to be discovered, but whose existence is beyond doubt. Indeed, dark matter halos explain very well the rapid motions of stars in peripheral regions of galaxies and also the relative motions of galaxies in large clusters. However, opinions about dark matter are not completely unanimous and there are scientists who seriously question its existence. Among other things, the properties that are assigned to the hypothetical matter are not able to explain some observations, such as, for example, the spatial distribution of the small satellite galaxies of the Milky Way or Andromeda. To name just one, the Czech astronomer Pavel Kroupa has spent more than a decade at the Max-Planck Institute (Bonn) criticizing what he considers to be a widely accepted dogma without the precise scientific rigor and even maintains a website dedicated to it. which he calls the dark matter crisis. LOST GALAXIES Another problem that dark matter encountered a decade ago concerned the number of satellite galaxies that a galaxy like the Milky Way should have. This is what was called "the problem of lost satellite galaxies". Computer simulations to reproduce the evolution of these types of galaxies surrounded by large halos of dark matter, indicated that there should be many more satellite galaxies than were observed. A reasonable agreement between theory and observations has recently been reached thanks to two factors. For one thing, observations with more powerful telescopes have revealed smaller and smaller galaxies. On the other hand, the models have been made more precise by including all the possible effects of ordinary matter that could suppress satellite galaxies: supernova explosions, jets ejected by black holes, etc. RECTIFYING NEWTON Among the alternatives that are handled to the dark matter hypothesis, perhaps the one with the most adherents, is the so-called "modified Newtonian dynamics", or simply MOND (for its acronym in English). According to this hypothesis, the motions of stars in galaxies and those of galaxies in clusters could well be explained by a modification of Newton's second law. However, before modifying such sacrosanct laws, the evidence should be overwhelming, something that at the moment is not. And that is why the MOND hypothesis has a very minor following among physicists and astrophysicists. THE SUBHALOS: A NEW CRISIS Now that the problem of lost satellite galaxies seemed to have found a remedy, a team of astronomers coordinated by Massimo Meneghetti (working at the Bologna Observatory, Italy, and at Caltech, USA) has uncovered another discrepancy between the dark matter models. and observations. This time the problem concerns large clusters of galaxies. Models predict that the distribution of dark matter in these superstructures cannot be very homogeneous. The halos that surround the galaxies and the dark material in the clusters must form irregular clouds, which have been called subhalos. The simulations come to predict the approximate number of subhalos that must exist in a given cluster. In order to count the actual number of dark subhalos (which, of course, are not visible), Meneghetti and his team have examined very precise images of various clusters that were taken by the Hubble space telescope and by ESO's large VLT telescopes. in the Chilean Atacama Desert. To count the subhalos, the astronomers looked at the amplification and distortion effects of light due to gravitational lensing. Indeed, the dark matter in each subhalo creates small arcs or multiple images, thus giving away its presence. The result of these observations is that the number of observed subhales is ten times higher than that predicted by the cosmological simulations. In a way, the problem is now the opposite of lost satellites. At that time, satellite galaxies were missing from the observations, whereas now subhalos are 'left over'. At the moment there is no explanation for this discrepancy posed by a new jug of cold water on dark matter. More and more precise observations will have to be made, but critics of the hypothesis are already sharpening their arguments. And MOND supporters raise their voices for cosmological simulations to be done by embedding MOND in models. The debate on dark matter thus takes on new momentum. More in The World KN95 masks will stop being sold in Spain from October The world Laura Pausini: "I am ashamed of Toñi Moreno" The world The results of Meneghetti and colleagues have been published just a few days ago in the prestigious journal Science. The manuscript can be consulted here. Rafael Bachiller is director of the National Astronomical Observatory (National Geographic Institute) and academic of the Royal Academy of Doctors of Spain.

Welcome!

To respond to fasting, cells use autophagy, a process of cellular self-recycling. Researchers at the University of Warwick in the UK have discovered how cells respond to fasting and activate a process called autophagy, which means that a healthier lifestyle can be promoted to help people maintain a healthy life. as published in the journal 'Cell Reports'. The UK has the highest level of obesity in Western Europe, and its levels have more than tripled in the last 30 years, it is estimated that more than half of the po[CENSORED]tion could be obese by 2050 in the UK. Obesity is a significant risk factor for increased morbidity and mortality. The cause of the rapid rise in obesity was attributed to modern lifestyles, including high-calorie diet. Intermittent fasting, alternate day fasting, and other forms of periodic calorie restriction have gained po[CENSORED]rity in recent years because they are considered beneficial for maintaining a healthy body weight. To respond to fasting, cells use autophagy, a process of cellular self-recycling. A team of researchers led by Professor Ioannis Nezis of the School of Life Sciences, University of Warwick, discovered how cells turn on autophagy genes during fasting. In the article, Dr. Anne-Claire Jacomin, Dr. Stavroula Petridi, PhD student Marisa Di Monaco, and Professor Ioannis Nezis have discovered proteins that are necessary for the transcription of autophagy genes. The proteins are called Sequoia, YL-1 and Sir2, these proteins interact with the protein related to cytoplasmic autophagy Atg8a. These interactions recruit Atg8a into the nucleus to control autophagy gene transcription. This is the first study to discover a nuclear role for the cytoplasmic protein Atg8a. The lead author of the research, Professor Ioannis Nezis, from the School of Life Sciences at the University of Warwick, explains that "understanding the molecular mechanisms of activation of autophagy genes during fasting will help us to use interventions to activate autophagic pathways to maintain normal body weight and promote healthy well-being. "

Considered a threat of domestic terrorism in the US, the movement creeps into radical opposition to Canadian Prime Minister Justin Trudeau The letter Q has become a symbol of the banners of the rallies of Donald Trump, president of the United States. Also appears on stickers, t-shirts and flag. So much paraphernalia reflects the po[CENSORED]rity of QAnon, a group that promotes conspiracy theories and that, could even soon have a representative on Capitol Hill. Canada, the neighbor to the north, navigates in different political waters, more prone to tolerance and consensus. However, it has not been reason enough to avoid the presence of QAnon in its territory. Born in October 2017 in online forums frequented by the American extreme right, QAnon has set the bar very high regarding nonsense and falsehoods. An individual named Q - the followers believe that he is an official with access to the greatest arcana - claims to have information about the existence of a global network of satanic pedophiles made up, among others, by members of the Democratic Party, Hollywood stars and millionaires. Furthermore, this malevolent group runs a "deep state" (with support from government personnel and the media) to take over the White House. However - and here QAnon supporters sigh in relief - Trump is fighting a secret war against these criminals whose final destination will be the cells of Guantánamo. QAnon soon gained a following in Canada; first in the catacombs of the internet; later, in social networks. At the end of 2018, hundreds of people protested in several Canadian cities (mainly in the provinces of Alberta, Manitoba and Saskatchewan) wearing yellow vests, emblem of the French movement that bears that name. Their criticisms were directed at the government of Justin Trudeau, whom they accuse of not supporting the oil industry with sufficient vigor and of being lax on immigration issues. Some protesters displayed the Q of QAnon, as well as WWG1WGA (initials in English: "where we go one, we all go", one of their best known slogans). For the first time, these symbols were strolling through the streets of Canada. Edwin Hodge, a sociology professor at the University of Victoria (British Columbia), studies conspiracy theories and far-right groups. For Hodge, one aspect that explains QAnon's presence on Canadian soil is the close cultural and digital contact between the United States and Canada, despite obvious political differences. Hodge also claims that many conspiracy movements emphasize narratives related to alleged projects on a global scale. "These movements, especially adaptable ones like QAnon, retain their appeal even when transplanted to other countries," she says. One of the most striking posters of the Canadian "yellow vests" -decorated with the Q- indicated: "Trudeau has sold us to the UN", in reference to the Global Compact for Migration in Marrakech, signed by Canada, but without legal ties and that it does not imply changes in migration policies. The most significant element of the Canadian supporters of QAnon consists in associating the liberal government (also at times with opposition parties and provincial authorities) with a supposed world agenda designed under the shadows. Thus, Justin Trudeau is considered an ally of the "deep state", in the same way as Angela Merkel. But Trudeau, according to followers of QAnon, also protects those pedophile circles that practice Satanism and is behind the death of Barry and Honey Sherman, the millionaires murdered in December 2017 in Toronto. Roxane Martel-Perron, educational director of the Center for the Prevention of Violent Radicalization in Montreal, comments: “There is strong interest in QAnon because of the alleged secret plans of governments, but it has also inspired unfounded allegations about pedophilia. It is enough to remember the case of harassment in social networks to a cafe in the Charlevoix region ”. Martel-Perron refers to an establishment in the town of Baie-Saint-Paul (Quebec) that last August received messages loaded with anger, since its logo is supposedly associated with pedophile groups. The pandemic has taken QAnon in Canada to another level. “Trudeau wants to impose communism. The restrictions due to covid-19 have nothing to do with the virus. ”, Appears on the wall of a Facebook group. Various demonstrations against the use of the mask have taken place in Canadian cities (Montreal, Ottawa, Vancouver, Calgary, Winnipeg). Several of the attendees have carried the Q and other references to QAnon.

Welcome

Welcome

Welcome!