₩ăřņîñĞ

Scientists say early experiments suggest it may one day be possible to make babies without using eggs. They have succeeded in creating healthy baby mice by tricking sperm into believing they were fertilising normal eggs. The findings in Nature Communications, could, in the distant future, mean women can be removed from the baby-making process, say the researchers. For now, the work helps to explain some of the details of fertilisation. End of mum and dad? The University of Bath scientists started with an unfertilised egg in their experiments. They used chemicals to trick it into becoming a pseudo-embryo. These "fake" embryos share much in common with ordinary cells, such as skin cells, in the way they divide and control their DNA. The researchers reasoned that if injecting sperm into mouse pseudo-embryos could produce healthy babies, then it might one day be possible to achieve a similar result in humans using cells that are not from eggs. In the mouse experiments, the odds of achieving a successful pregnancy was one in four. Dr Tony Perry, one of the researchers, told the BBC News website: "This is the first time that anyone has been able to show that anything other than an egg can combine with a sperm in this way to give rise to offspring. "It overturns nearly 200 years of thinking." Those baby mice were healthy, had a normal life expectancy and had healthy pups of their own. Fertilisation The goal of the researchers is to understand the exact mechanisms of fertilisation because what happens when a sperm fuses with an egg is still a bit of a mystery. For example, the egg completely strips the sperm's DNA of all its chemical clothing and re-dresses it. That stops the sperm behaving like a sperm and makes it act like an embryo, but how the "costume change" takes place is not clear. Removing the need for an egg could have a wider impact on society. Dr Perry said: "One possibility, in the distant future, is that it might be possible that ordinary cells in the body can be combined with a sperm so that an embryo is formed." In other words, two men could have a child, with one donating an ordinary cell and the other, sperm. Or one man could have his own child using his own cells and sperm - with that child being more like a non-identical twin than a clone. Dr Perry stressed that such scenarios were still "speculative and fanciful" at this stage. Earlier this year in China, scientists were able to make sperm from stem cells and then fertilise an egg to produce healthy mice. Dr Perry suggested that combining the two fields of research may eventually do without the need for sperm and eggs altogether. Prof Robin Lovell-Badge, from the Francis Crick Institute, commented: "I'm not surprised that the authors are excited about this. "I think it is a very interesting paper, and a technical tour de force and I am sure it will tell us something important about reprogramming at these early steps of development that are relevant to both fertilisation and single cell nuclear transfer [cloning]. "And, perhaps more broadly, about reprogramming of cell fate in other situations. "It doesn't yet tell us how, but the paper gives a number of clear pointers."

American Truck Simulator GAMEPLAY – Parking Challenge American Truck Simulator! Reverse-parking a massive trailer can’t be that hard, right? Wrong. It’s hard as nails. So Jim made his colleagues attempt it, mainly to upset them. The winner will shock you. Maybe. Reverse parking 30 tons of American haulage is not easy. https://www.youtube.com/watch?v=T9gjb4iL-9M&feature=youtu.be

After a rough and underwhelming return to the gruelling Dakar rally in 2015, Peugeot Sport slinked back to its secret bunker and set to work on the next iteration of its off-road monster. Earlier this year, that went and stomped the two-week off-road endurance race serving Stéphane Peterhansel his 12th Dakar victory. For next year’s race, Peugeot Sport has gone back to the drawing board and built an all-new car. No longer based on the hum-drum 2008 crossover, for Dakar 2017 Peugeot are using the bigger 3008 SUV that’s set to debut at the upcoming Paris motor show as a basis. But don’t worry, it’s still about as 3008-y as the old 2008 DKR was 2008-y. Due to that dastardly rule book, the dimensions of the 3008 DKR haven’t changed compared to its predecessor. Yes, it’s still longer and wider than the unstable first generation DKR car, but the footprint is no different to the current car – which has proven to be a lot better at ironing out South America’s undulations. You may also notice it’s quite squat. That’s to help lower the centre of gravity. Something those two spare tyres that are hidden in its cheeks also helps with. And those short overhangs at the front and back allow it to bash and crawl up and over pretty much everything it can get its thick tyres onto. Apparently, the main areas of improvement over the old car are reliability and driveability. Both crucial elements given the DKR’s bread and butter is to compete in a race that’s 10,000 kilometres long, pretty much flat-out and takes place in every weather condition Earth can throw at it. The 3.0-litre mid-mounted V6 twin-turbo diesel engine now delivers greater amounts of crucial torque at lower revs. This wasn’t easily achieved given there’s been a rule change imposing a smaller restrictor on the engine (38mm as opposed to 39mm), sapping around 20 horsepower. The dampers and suspension geometry have also been further honed to provide a more stable and better ride for pounding across the desert. Plus, the air con system has been upgraded to make sure the driver and navigators don’t boil in their race suits. But Peugeot is still going against the grain of its top-level competitors by sticking to a two-wheel drive layout instead of four. Which means all 330bhp and 590lb ft of torque heads to the rear wheels. Which means lots of sandy skids. But there’s more to it than that. With no power heading to the front wheels, there are less mechanical connections to potentially fail. It also keeps the 3008 DKR in a less restrictive class, loosening up the regulations to which Dakar’s dominant four-wheel-drive competitors must adhere. So that updated suspension offers a hell of a lot more travel than four-wheel-drive cars (460mm against 250mm), it can run bigger wheels, plus a trick inboard remote tyre-pressure system that allows the car to inflate/deflate its rubber on the move. Will the 3008 DKR help revive Peugeot’s Dakar dominance of old? Well, they have an off-road dream team of drivers – Stéphane Peterhansel, Carlos Sainz, Sébastien Loeb and Cyril Despres – which helps. But we’ll just have to wait until January to find out for sure.

Three Syrian men have been arrested in Germany on suspicion of being sent by so-called Islamic State (IS) to launch attacks, prosecutors say. The men - aged between 17 and 26 - were detained after a series of pre-dawn raids in the states of Schleswig-Holstein and Lower Saxony on Tuesday. Later, Interior Minister Thomas de Maiziere told journalists the suspects may have had links to the men who attacked Paris in November last year. He called the three a sleeper cell. The Federal Public Prosecutor's office has said no concrete missions or orders have so far been found, despite the seizure of "extensive material". The men - identified only as Mahir al-H, 17, Ibrahim M, 18, and Mohamed A, 26 - are said to have travelled through Turkey and Greece on false passports. Investigators believe they had volunteered for the alleged mission, and that the 17-year-old had been trained in handling weapons and explosives in Raqqa, IS's stronghold in Syria. They received fake passports, mobile phones loaded with a pre-installed communication programme and four-figure cash sums in US dollars. 'On edge' The men were arrested when 200 police and security officers raided six locations, including three refugee shelters. Investigations so far suggest the three came to Germany in November 2015 with the intention of "carrying out a previously determined order [from IS] or to await further instructions", prosecutors said in a statement. Suspicions of the men were first raised months ago, and the men had been under surveillance including phone-tapping for weeks, reported the German news agency DPA. Football fans gather on the field of the Stade de France stadium after explosions during a friendly football match between France and Germany in Saint-Denis, north of Paris, on 13 November 2015 - one of a number of deadly attacks on the night At a news conference, Mr Maiziere said they were trafficked into Europe by the same organisation that supported the three men who blew themselves up outside the Stade de France national football stadium in Paris on 13 November. A bystander also died - one of the total of 130 people killed in a series of co-ordinated attacks that night. Paris attacks: Who were the attackers? Germany is on edge after a spate of attacks over the summer, says the BBC's Jenny Hill in Berlin. Over one week in July, 10 people were killed and dozens more wounded in separate gun, bomb, axe and machete attacks in the south of the country. Islamic State appeared to play a role in two of those attacks, by asylum seekers in Wuerzburgand Ansbach. In both cases, the attackers were killed. In early June, three Syrian men were arrested on suspicion of plotting an IS suicide attack in the western city of Duesseldorf. Tuesday's arrests are likely to be welcomed by ministers who are trying to reassure Germans that they can keep the country safe, our correspondent adds. The government has been under pressure to reduce the number of refugees it admits - more than a million in 2015 - under Chancellor Angela Merkel's "open-door" policy.

v1- text , effect !

===================================================================== ============================================================================================= =========================================================================================

Smart phones are no longer an avenue for entertainment, but could be used for medical purposes, such as the monitoring of minute heartbeat and measuring calories during sports, in recent times, a British company has developed a clever way to test blue water disease of the eye. And developed a team of Cambridge kansiltnt ", a company specializing in technology, applying the telephone associated with virtual reality goggles like device for testing the safety of eye disease. The device allows testing was required to go to the hospital, which bodes well for a promising potential treatment, especially in areas where there is no doctors specialists in ophthalmology. Blue water is or "glaucoma" genetically caused disease glaucoma, affects those over 45 years of age in particular, and may lead to blindness. According to the site "digital trand, the new device costs only $ 25 and therefore is cheaper than a currently approved device in hospitals. The device can be used easily, with enough put it on the eye, and then hold the remote control in hand, and when a Flash of light gun for the tempter, he presses the buttons, just 5 minutes gets the result, and would be able, then, to consult a doctor.

V2 Text , Blur , Broder !

The Killing Floor 2 Tactical Response update is now live, bringing new SWAT perks and weaponry to the game, a new map, tweaks to existing perks and Zed resistances, plus new achievements and loyalty rewards. The SWAT perk adds the FN P90, MP7, MP5RAS, and Kriss Vector submachineguns to the game, along with a flashbang grenade that carries a high chance of stunning Zeds, and a tactical knife, for when the situation gets really out of hand. Which seems to be pretty much always. A new “elite” variant of the Horzine Security Armor and Horzine 9mm pistol will also be given to everyone who plays Killing Floor 2 during early access, and there's a new set of "cardboard armor" that will be available for purchase in a new cosmetic bundle. The new map, called Infernal Realm, is actually a community creation that's been adopted into the official lineup. The title offers a pretty good hint of what to expect, as players will face off against Zeds “surrounded by bones, hanging corpses, brimstone, and hellfire. And the trader is a totem made of bones. That can't be a good sign.” Almost all of the pre-existing perks have been tweaked to some extent, but Tripwire said Firebug, Support, and Medic were given more attention than most in order to better balance their skills. “Zeds have also had their resistances revised, their movement and evasion tactics made more challenging, and their spawn groups adjusted, creating a much more intense experience on higher difficulty levels,” it said. “And watch out for Hans. Really. He's been at the gym or something.” The full Killing Floor 2: Tactical Response update changelog is available on Steam.