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The blockbuster drugs Ozempic and Wegovy may help people cut back on drinking, new research published Wednesday in JAMA Psychiatry suggests. In a study of around 228,000 people in Sweden who had alcohol use disorder, researchers found that people who were taking a GLP-1 drug like semaglutide were less likely to be hospitalized for alcohol-related issues. Just over 28 million adults in the U.S. have alcohol addiction, according to the National Institute on Alcohol Abuse and Alcoholism. Only three medicines, however, are approved to treat it. “The pharmacological treatments available for AUD are not very good, and relapse is really common,” said Alex DiFeliceantonio, an assistant professor at Virginia Tech’s Fralin Biomedical Research Institute. The study leader, Dr. Markku Lähteenvuo, a psychiatric researcher at Niuvanniemi Hospital in Finland, said: “I see so many patients who do not have good outcomes on the medications we have and who are desperate for help with their addiction. We really do need more tools in the toolbox.” GLP-1 drugs — the class of medication that includes semaglutide and other po[CENSORED]r drugs like tirzepatide — have shown potential for treating addiction. A clinical trial published in 2022 found that an older GLP-1 drug called exenatide reduced drinking, but only among those who had both alcohol use disorder and obesity. Several other studies have examined drinking habits among people taking GLP-1 drugs who do not have alcohol use disorder. In the new study, Lähteenvuo and his team looked at medical records from 228,000 people in Swedish who were diagnosed with alcohol use disorder from 2006 to 2023. All of the people in the study also had obesity or Type 2 diabetes. Ozempic and Wegovy may help curb alcohol addiction, study suggests

More than half of Senate Republicans, including some in senior leadership positions, privately say they don’t see a path for former Rep. Matt Gaetz, R-Fla., to be confirmed as attorney general and would not support him to lead the Department of Justice, according to multiple people who spoke to NBC News on condition of anonymity. While Gaetz’s ability to be confirmed appears on the rocks among Senate Republicans, President-elect Donald Trump’s team remains confident he will eventually be confirmed, even if it’s after an ugly battle. NBC News spoke to more than 15 additional Republican sources who agreed that there are not enough votes in the Senate to confirm Gaetz, and some estimated that closer to 30 Republicans consider him unqualified. Gaetz and Trump attorney Todd Blanche are moving full speed ahead on trying to fill out the Justice Department, according to sources familiar with the planning. If confirmed, Blanche would serve in the powerful No. 2 position at the Justice Department, overseeing all U.S. attorney’s offices throughout the country. “President Trump and his team are focused on and confident in the confirmation of AG-designee Gaetz,” a person familiar with Trump’s thinking told NBC News. Vice President-elect JD Vance and his aides have also been working the phones over the last two days to get a read on where senators stand on Gaetz. Trump announced he was choosing Gaetz for the attorney general role on Wednesday, writing in a post on Truth Social, “Few issues in America are more important than ending the partisan Weaponization of our Justice System. Matt will end Weaponized Government, protect our Borders, dismantle Criminal Organizations and restore Americans’ badly-shattered Faith and Confidence in the Justice Department.” When the president-elect initially publicized his pick, many Republicans — except for House Speaker Mike Johnson, who got a heads-up from Trump — were in complete shock. In his few terms in the House, Gaetz has often been embroiled in controversy. He was investigated by the Justice Department in a case involving the alleged sex trafficking of a 17-year-old girl, though the former congressman, who resigned his post shortly after he was picked for attorney general, has always denied the allegations and has never been criminally charged. On Thursday, though, a lawyer for the 17-year-old girl wrote in a post on X, saying, “She was a high school student and there were witnesses” when the alleged incident occurred. The attorney, John Clune, also called for the release of a House Ethics Committee report detailing the committee’s investigation into Gaetz, which has been ongoing for several years. “If they want to send [the report] that’d be fine,” Sen. Lindsey Graham, R-S.C., a staunch Trump ally, told reporters at the Capitol this week, though he added in a statement from his office that he planned to vote to confirm each of the president-elect’s judicial nominees. On Friday, Johnson said he would “strongly request” that the report not be released publicly, though several Republican senators have said they would like to view the report as part of their deliberation process ahead of a confirmation vote. “I don’t want there to be any limitation at all on what the Senate can consider,” Sen. John Cornyn, R-Texas, told reporters at the Capitol this week when asked whether the Senate Judiciary Committee should be privy to the report. “We need to have a complete vetting of the nominees, not only so we know that the nominee is qualified, but also to protect the president,” he added. “I think when you’re at this point, particularly given his abrupt departure from Congress just prior to that report coming out, considering the job that he is being appointed to, considering that the FBI is going to do a background check anyway, I can’t imagine that the committee is not going to want to see it,” said Sen. Kevin Cramer, R-N.D. “So, at the very least, those of us that will have a vote at some point, starting with the Judiciary Committee, should see that. And I can’t imagine they won’t.” The House Ethics Committee was expected to meet on Friday to decide whether to release its report on Gaetz, whom it has been investigating on and off since 2021, according to a source with direct knowledge. The panel abruptly canceled the meeting, which House Ethics Committee Chair Michael Guest, R-Miss., insisted was only postponed. Later on Friday, an attorney for another woman interviewed by the House Ethics Committee said that his client “testified to the House Ethics Committee that she witnessed Rep. Gaetz having sex with a minor at a house party in Orlando in 2017.” Several Republicans shared that Gaetz, who was investigated by the very agency he could now oversee, has a “steep hill” to climb toward confirmation in the Senate. “I would guess if we had a vote today on the Senate floor, it might be more than that,” Cramer said Thursday when pressed whether 10 Senate Republicans could vote to oppose Gaetz — as Democratic Sen. Richard Blumenthal suggested to NBC News earlier that day. “I have concerns that he can’t get across the finish line, and we’re gonna spend a lot of political capital … on something that even if they got it done, you’d have to wonder if it was worth it.” A majority of Senate Republicans doubt Matt Gaetz will be confirmed as attorney general, sources say

A second-half blitz saw England sweep past 10-player Republic of Ireland 5-0 at Wembley to clinch promotion back to League A of the Nations League in Lee Carsley's final game as interim manager. Three goals in just six minutes at the start of the second half from Harry Kane - via a penalty in an incident that saw Ireland defender Liam Scales sent off after a second caution - followed by maiden strikes from Anthony Gordon and Conor Gallagher blew the visitors away. Jarrod Bowen soon added a fourth with his first touch after coming on as a substitute, before Taylor Harwood-Bellis headed home a fifth as a third player got off the mark for the Three Lions. How England's second-half blitz blew Republic away: Ireland had initially done an excellent job to largely frustrate England in a feisty first half that ended with Carsley's side having 75 per cent possession, but without having tested visiting goalkeeper Caoimhin Kelleher. England 5 - 0 Rep Ire - Match Report & Highlights

The Exploration Company (TEC) announced Monday it has raised $160 million to fuel development of its capsule that is designed to take astronauts and cargo to space stations. Venture capital firms Balderton Capital and Plural were the lead investors in the round which also included French government-backed investment vehicle French Tech Souveraineté and German government-backed fund DeepTech & Climate Fonds. TEC’s core product is Nyx, a capsule that can be launched from rockets into space carrying passengers and cargo. Nyx is reusable so once it has dropped its payload, it can re-enter the Earth’s atmosphere and be used for the next mission. “It’s a big market, and it’s growing about a bit more than 10% per year because more nations want to fly their astronauts and more nations want to go to the moon,” Hélène Huby, founder and CEO of TEC, told CNBC in an interview. “So there is an increased demand for sending people to stations, sending cargo to stations,” she said. This part of the market has very few players. Some of the biggest are SpaceX which has a capsule called Dragon. There are also rivals from China and Russia. “We said, ’okay, let’s build this capacity in Europe so that Europe can have its own capsule and also the world needs an alternative solution. [We] cannot only bet on SpaceX,” Huby said. TEC is currently developing the second version of Nyx which it expects to launch next year, followed by a final version in 2028. This model will be partly financed by the European Space Agency. Huby said the company has signed $800 million in contracts to use its capsule. These include mission contracts with companies including Starlab, which is designing a new space station, and Axiom Space. There is increasing activity in space among nations including China, the U.S. and India. One of the most ambitious projects is the NASA-led Gateway, which will be the first space station to orbit the moon. “If you have more people, you also have a need for more cargo. So this is what is happening around the Earth and around the moon,” Huby said. Huby sees TEC being a key player when it comes to developing the technology that is needed to return cargo to Earth once it has been in space. “This is also where we where we believe our vehicle is going to play an important role,” Huby said. SpaceX rival TEC raises $160 million for reusable space capsule

Nick movie: El Camino: A Breaking Bad Movie Time: 2019 Netflix / Amazon / HBO: Netflix Duration of the movie: 2h 2m Trailer:

Live Performance Title: Counting Stars Signer Name: OneRepublic Live Performance Location: Festhalle, Frankfurt Official YouTube Link: Your Opinion About the Track (Music Video): 10/10

Musician Name: James Burgon Valentine Birthday / Location: October 5, 1978 (age 46 years), Lincoln, Nebraska, United States Main instrument: Guitar Musician Picture: Musician Awards & Nominations: - Best Performance: Sugar Other Information: -

Artist: Ryan Tedder Real Name: Ryan Benjamin Tedder Birth Date / Place / Age: June 26, 1979 (age 45 years), Tulsa, Oklahoma, United States Social status (Single / Married): Married Artist Picture: Musical Genres: Pop Awards: Grammy Award for Album of the Year 2012 Top 3 Songs (Names): Counting Stars / Good Life / Secrets Other Information: -

Music title: Maps Signer: Maroon V Release date: 2014 Official YouTube link:

¤ Nickname: [noor]<>???????<>MAX ¤ Date / Time: Now ¤ IP Address/SteamID: 156.217.87.122 | STEAM_1:0:1013184766 ¤ Ban Duration: Permanently ¤ Reason: Blacklisted. (Permanently)

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