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https://www.bbc.com/news Japan has put a batch of Moderna's Covid-19 vaccine on hold after a foreign substance was found in a vial. A pharmacist saw several black particles in one vial of the vaccine in Kanagawa Prefecture, according to authorities. Some 3,790 people had already received shots from the batch. The rest of the batch has now been put on hold. It comes less than a week after Japan suspended the use of about 1.63 million Moderna doses due to contamination. The pharmacist found the black particles while checking for foreign substances before the vaccine's use. The jab's domestic distributor has collected the vial suspected to be contaminated. Local media reports say there is no evidence so far of any health hazards caused by the potentially contaminated vaccine. Takeda Pharmaceutical, which sells and distributes the vaccine in Japan, had just last week put three batches of the vaccine on hold after "foreign materials" were found in some doses of a batch of roughly 560,000 vials. Spanish pharmaceutical firm Rovi, which bottles the vaccine, said in a statement that a manufacturing line in Spain could be the cause of the issue. It added that it was conducting an investigation. On Tuesday, Japan's health minister said foreign matter found in jabs in the southern prefecture of Okinawa were due to needles being incorrectly inserted into vials. Japan is battling a spike in Covid cases while it hosts the Paralympic Games. Its vaccination roll-out has been relatively slow, with just over 40% of Japanese people fully vaccinated and around 50% having received one dose.

https://www.livescience.com/ An encounter with one of these reptiles could cost you your life. They hiss, they slither and unfortunately for humans and unsuspecting prey, they bite. Snakes bite about 5.4 million people every year, resulting in between 81,000 and 138,000 deaths, according to the World Health Organization. Venomous snakes kill their victims with toxic substances produced in a modified salivary gland that the animal then injects into prey using their fangs. Such venom has evolved over millions of years to cause severe reactions in the victim, from immobilization and hemorrhage to tissue death and inflammation, researchers reported in 2019 in the journal Frontiers of Ecology and Evolution. Here are 10 snakes whose venom not only packs a punch for small prey but that can take out humans. Africa's deadliest snake, the black mamba (Dendroaspis polylepis) can kill a person with just two drops of venom, Live Science reported. Named for the dark, inky color inside of their mouths, black mambas are actually brownish in color. They average around 8 feet (2.5 meters) in length, and can move at 12 mph (19 km/h). The lengthy snakes are born with two to three drops of venom in each fang, so they are lethal biters right from the get-go. By adulthood, they can store up to 20 drops in each of their fangs, according to Kruger National Park. Without treatment, a bite from this African snake is just about always lethal. Here’s what a black mamba’s venom does to your body: Once injected, the venom interferes with activity at a junction where nerves and muscles connect, resulting in paralysis, Ryan Blumenthal, of the University of Pretoria, reported in The Conversation. Because the venom is also cardiotoxic, it can lead to cardiac arrest. That was the case for a South African man who got bitten by a black mamba on his index finger, Blumenthal reported. By the time he got to the hospital, within 20 minutes, he was already in cardiac arrest. Even though doctors treated him with antivenom, the man ended up dying days later, Blumenthal said. Scientists aren't sure how many people are killed every year by black mamba, but Blumenthal estimates it is responsible for the largest number of snake-related deaths in southern Africa. A bite from a fer-de-lance (Bothrops asper) can turn a person's body tissue black as it begins to die, according to a 1984 paper published in the journal Toxicon. These pit vipers, which live in Central and South America and are between 3.9 and 8.2 feet (1.2 and 2.5 m) long and up to 13 pounds (6 kg), are responsible for about half of all snakebite venom poisonings in Central America, according to a 2001 study published in the journal Toxicon. Because fer-de-lance venom contains an anticoagulant (a substance that hinders blood clotting), a bite from this snake can cause a person to hemorrhage. And if that didn't scare you off, consider this: A female can give birth to 90 fierce offspring, according to the University of Costa Rica. About 24 hours after being bitten on the thumb by a juvenile boomslang (also called a South African green tree snake), herpetologist Karl Patterson Schmidt died from internal bleeding from his eyes, lungs, kidneys, heart and brain, researchers reported in 2017 in the journal Biochimica et Biophysica Acta. The snake had been sent to Schmidt at The Field Museum in Chicago for identification. Like others in the field at the time (1890), Schmidt believed that rear-fanged snakes like the boomslang (Dispholidus typus) couldn't produce a venom dose big enough to be fatal to humans. They were wrong. The boomslang, which can be found throughout Africa but lives primarily in Swaziland, Botswana, Namibia, Mozambique and Zimbabwe, is one of the most venomous of the so-called rear-fanged snakes, according to the University of Michigan Museum of Zoology. Such snakes can fold their fangs back into their mouths when not in use. As in other deadly snakes, this one has hemotoxic venom that causes their victims to bleed out internally and externally, the Museum reported. Advertisement With an egg-shaped head, oversized eyes and a bright-green patterned body, the boomslang is quite the looker. When threatened, the snake will inflate its neck to twice its size and expose a brightly colored flap of skin between its scales, according to the South African National Biodiversity Institute. Death from a boomslang bite can be gruesome. As Scientific American describes it: "Victims suffer extensive muscle and brain hemorrhaging, and on top of that, blood will start seeping out of every possible exit, including the gums and nostrils, and even the tiniest of cuts. Blood will also start passing through the body via the victim's stools, urine, saliva, and vomit until they die." Luckily, there is antivenom for the boomslang if a victim can get it in time. Native to the mountains and grasslands of southeast Australia, the eastern tiger snake (Notechis scutatus) is named for the yellow and black bands on its body, though not all po[CENSORED]tions sport that pattern, according to the Australian Museum. Its potent venom can cause poisoning in humans in just 15 minutes after a bite and is responsible for at least one death a year on average, the University of Adelaide reported. Around 58,000 deaths in India are attributed to snake bites every year, and the Russell's viper (Daboia russelii) is responsible for the majority of these mortalities, according to research published March 25, 2021, in the journal PLOS Neglected Tropical Diseases. This species is considered one of the most deadly of the true vipers, researchers reported in 2021 in the journal Toxins. In Sri Lanka, where this nocturnal viper likes to rest in paddy fields, they cause high mortality among paddy farmers during harvest time. The snake's venom can lead to an awful smorgasbord of symptoms: acute kidney failure, severe bleeding and multi-organ damage, researchers reported in the Handbook of Clinical Neurology in 2014. Some components of the venom related to coagulation can also lead to acute strokes, and in rare cases, symptoms similar to Sheehan's syndrome in which the pituitary gland stops producing certain hormones. Victims typically die from renal failure, according to the handbook. The saw-scaled viper (Echis carinatus) is the smallest member of the "Big Four" in India — along with Russell's viper, the common krait (Bungarus caeruleus) and the Indian cobra (Naja naja) — thought to be responsible for the most bites and related deaths in the country. Rather than the stereotypical "hissing" sound attributed to snakes, this viper starts "sizzling" by rubbing together special serrated scales when threatened, according to research published in 2013 in the Journal of Venomous Animals and Toxins including Tropical Diseases, according to a journal statement. Once bitten by this viper, a person will have localized swelling and pain in the area, followed by potential hemorrhage. Since the venom messes with a person's ability to clot blood, it can lead to internal bleeding and ultimately acute kidney failure, according to the educational society Understanding Animal Research. Hydration and antivenom (there are nine types of antivenom for this snake) should be administered within hours of the bite for a person to survive, Understanding Animal Research said. The banded krait (Bungarus fasciatus) is a slow mover during the day and is much more likely to bite after dark. The snake's venom can paralyze muscles and prevent the diaphragm from moving, according to a 2016 study published in the journal PLOS Neglected Tropical Diseases. This stops air from entering the lungs, effectively resulting in suffocation. The king cobra (Ophiophagus hannah) is the world's longest venomous snake, measuring up to 18 feet (5.4 m), according to the Natural History Museum in London. The snake's impressive eyesight allows it to spot a moving person from nearly 330 feet (100 m) away, according to the Smithsonian Institution. When threatened, a king cobra will use special ribs and muscles in its neck to flare out its "hood" or the skin around its head; these snakes can also lift their heads off the ground about a third of their body length, according to the San Diego Zoo. Its claim to fame is not so much the potency of its venom, but rather the amount injected into victims: Each bite delivers about 7 milliliters (about 0.24 fluid ounces) of venom, and the snake tends to attack with three or four bites in quick succession, the Fresno Zoo reported. Even a single bite can kill a human in 15 minutes and an adult elephant in just a few hours, Sean Carroll, molecular biologist at the University of Maryland, wrote in The New York Times. You could be bitten multiple times before becoming aware of the coastal taipan (Oxyuranus scutellatus), thanks to its incredible speed, according to the Australian Museum. When threatened, this snake, which lives in the wet forests of temperate and tropical coastal regions, will lift its whole body off the ground as it jumps fangs-first with extraordinary precision and injects venom into its enemy. Before 1956, when an effective antivenom was produced, this snake's bite was nearly always fatal, according to Australian Geographic. The inland taipan is the one of the most venomous snakes, according to the International Journal of Neuropharmacology, meaning just a teensy bit of its venom can kill prey (or human victims). They live tucked away in the clay crevices of Queensland and South Australia'a floodplains, often within the pre-dug burrows of other animals. Living in more remote locations than the coastal taipan, the inland taipan rarely comes into contact with humans, the Australian Museum reported. When the taipan does feel threatened, the snake coils its body into a tight S-shape before darting out in one quick bite or multiple bites. A main ingredient of this venom, which sets it apart from other species, is the hyaluronidase enzyme. According to a 2020 issue of Toxins journal (Novel Strategies for the Diagnosis and Treatment of Snakebites), this enzyme increases the absorption rate of the toxins throughout the victim's body. name for all snakes 10. Black mamba 9. Fer-de-lance 8. Boomslang 7. Eastern tiger snake 6. Russell's viper 5. Saw-scaled viper 4. Banded krait 3. King cobra 2. Coastal taipan 1. Inland taipan

The new 'Adaptive Volume' feature is available in the US. Amazon has rolled out a new feature for Alexa that can make sure you hear what the voice assistant says even while the TV's on or while people are talking. According to The Verge, the new feature called Adaptive Volume will make Alexa speak louder if it detects a lot of ambient noise. The goal, the company told the publication, is for you to be able to hear the voice assistant's responses over the noise in your home or office. If you're outside the US, though, you won't be able to give it a try just yet — The Verge says it's only available for US customers at the moment. The publication tested the feature using an Echo Dot that's right next to a desktop PC with a spinning fan and found its performance inconsistent. Alexa responded in a louder than usual voice at times, but other times it replied in its usual volume. It's possible that the company is still fine-tuning the feature before making it available in other regions. The Verge has also noted that Amazon didn't say whether Adaptive Volume can also make the voice assistant respond in a quieter voice if it detects almost no ambient noise. Alexa has long had a "whisper mode," however, which can make it respond in a softer voice when you whisper commands to it. If you're in the US and want to give Adaptive Volume a try, simply activate it by saying "Alexa, turn on adaptive volume."

For many kids, this year means a return to the physical classroom, while parents scour for supplies, clothes and whatever else they might need for the start of a new school year. It also means once again juggling homework, assignments, extracurricular activities and so on. Luckily, we have some tech that can help. There are many apps out there both kids and parents can use to help them adjust, whether it's tools to learn or to stay organized. Here's a look at some you should consider downloading: —Quizlet. Instead of writing out piles of flash cards, why not make them readily accessible on your mobile device? This app lets users you make digital flash cards across a variety of subjects such as math, languages, science and more. —Photomath. An ideal app for both kids and parents (especially this pre-algebra-challenged journalist), Photomath lets you take pictures of math problems and then solves them. Along with each solution, the app will also take you step by step through how the problem was solved. —Socratic. The Google-powered learning app lets you plug in questions either by text, audio or photo across a range of different subjects. Like with Photomath, you submit math problems to solve, or add questions or topics and the app spits out the appropriate response. It might come in the form of a Wikipedia page, a YouTube video, or a solution from another app. —myHomework. Need help keeping school work organized? The myHomework app for laptops, tablets and smartphones is a planner allowing students to keep track of their classes and assignments. —Duolingo. The po[CENSORED]r language learning app can help users who are studying Spanish, French, German and countless other languages with smaller mini-games. If you've got younger kids, the company also has Duolingo ABC, which helps teach kids how to read and write in English. —Epic! Perfect for elementary school kids who love reading. The Epic app features thousands of books at all different age groups and reading levels. The app's Basic account offers users one free book a day from a smaller library. The Unlimited option for $9.99 a month includes more than 40,000 books as well as audiobooks and "read-to-me" books where the app will read the book to your child. —Fantastical. My personal favorite calendar app. It integrates with most third-party calendars and gives users elegant views of their day-to-day schedules and breakdowns of the month, and even incorporates weather details. —Any.do. If you need some extra organization, this tasks app can help users stay on top of daily tasks as well as plan tasks beyond today. Great if you're a parent who needs to keep tabs on kids' school time and extracurricular activities. If you want an alternative, there's also Microsoft To Do, formerly known as Wunderlist.

All of the laptops with Nvidia’s RTX 3070 GPU. NVIDIA’s RTX 3070 is a seriously capable laptop gaming GPU — armed with 5,120 CUDA cores, 8GB GDDR6 video memory and a boost clock speed up to 1,620 MHz. Regardless of how good the graphics card is, you may have a challenge finding portable systems sporting one. That’s why we’re doing this big round up of all the major-brand RTX 3070 laptops you can buy (in the U.S.), along with links to where you can pick one up. A quick disclaimer: we have not tested all of these laptops, so we won’t be talking about their overall performance; for that, we maintain a list of the best gaming laptops overall, which includes some RTX 3070 models. But since stock issues continue -- both for the best graphics cards and the systems that contain them -- sometimes your top choice is the one you can find for sale today. These options come with both Intel or AMD CPUs, so you’re covered whatever processor you prefer. And with stock, pricing and shipping times changing rapidly, we can’t 100% guarantee that something on this list will still be available by the time you read this. But rest assured, we will be keeping up to date as regularly as possible.

If something or someone exists there's no reason why it can't be in Fortnite. In terms of likelihood, I'd rate Will Smith's new appearance in Fortnite on the "likely" end of the scale, because it's not as weird as, say, Martin Luther King's 'I have a dream' speech airing in the whimsical promotional vehicle-slash-videogame about murdering other players. Plus: a dataminer unearthed the skin last month. It's not really a Will Smith skin by the way: it's a skin of the actor's Bad Boys character Mike Lowery. It's available in the Fortnite Item Shop, and includes the Detective's Duffle Back Bling and a dual-wielding pickaxe called the Loose Cannon Cutters. I'm sure there are rich lore reasons why it's called that. Why is Will Smith (or Mike Lowrey) in Fortnite all of the sudden? Does there need to be a reason? As far as I can tell there isn't one. Season 7 Chapter 2 is themed around aliens, and as several other sites have pointed out, Mike Lowrey doesn't fight aliens, never has, though plenty of Smith's other film characters do. Anyway, you can now be Will Smith in Fortnite and that's something. Lately, skins for Morty, Wonder Woman and Ariana Grande have been added to the game.

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➥Age:16 ➥Contact(Steam, TS3, Discord etc): dhiamerniz#4990 ➥Experience in Adobe Photoshop(Months or years):new ➥Obligatory attach your Gallery link (If you have one): here ➥Any other editing program you use?:no only photoshop ➥What version of Photoshop do you use?:last ➥In what section you have your most contribution?::i am starting ➥Have you read all the rules from each section?:yes ➥How many hours you want to dedicate to forum & gfx?:2-3 h ➥Do you agree that once accepted, you need dedicate a few hours of your daily time to the forum/gfx/ts3:yes ➥Do you agree that once accepted, we as a team need to communicate more so we know each other's time:yes ➥Do you agree that once accepted, we 100% need a way of contacting you, either is from forum's PM, TS3, Discord or any other contact method:yes ➥What can you say about you that will make us interested about your Photoshop skills & experience?(Minimum 10 words):Well, this is a little new, but with the passage of time I hope to learn and also hope to help you