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At least 140 people were killed, most of them civilians, in the attack on 8 October - one of the single worst death tolls in the two-year conflict. An inquiry blames "non-compliance with coalition rules of engagement" and "the issuing of incorrect information". The attack was heavily criticised internationally. The 14-nation Saudi-led inquiry, carried out by the Joint Incidents Assessment Team, said coalition aircraft were wrongly told that the funeral hall was full of Houthi leaders. It said "a party affiliated to the Yemeni presidency of the general chief of staff" was to blame. The inquiry also apportioned blame to the Air Operation Center in Yemen for directing aircraft onto the target without obtaining approval from the coalition's command. The investigation called for families of the victims to be compensated. An estimated 600 people were injured in the bombing. "Coalition forces must immediately review their rules of engagement and update their procedures to ensure adherence in future," the inquiry team said. Growing pressure to end war: Frank Gardner, BBC Security Correspondent The findings of this Saudi-led investigation will come as no surprise and little consolation to those caught up in the devastating air strike on a funeral in Sanaa. Already social media postings have suggested that blaming a senior Yemeni military officer for ignoring the rules is a case of scapegoating. But for Saudi Arabia, which was already looking for ways to extricate itself from the Yemen conflict, this could be a watershed moment. Beyond sacking those responsible for this catastrophic breach of its targeting rules and compensating the victims' families, the Saudi-led coalition is immediately reviewing its rules of engagement. Will this be enough to silence those calling for the UK and US to curb their arms sales to Saudi Arabia? Unlikely. As long as air strikes continue over Yemen civilians will continue to die, while Houthi rebels continue to fire their missiles across the border at Saudi villages. So the pressure to end this unwinnable war is greater than ever. One woman's lonely struggle against famine in Yemen A year of war that has set Yemen back decades Practising medicine under fire in Yemen The conflict in Yemen pits forces loyal to the internationally recognised government of President Abdrabbuh Mansour Hadi against Houthi rebels. The coalition led by Saudi Arabia accuses Iran of backing the rebels and supports the president. Yemen crisis: Who is fighting whom The United Nations says more than 6,000 people have been killed in the conflict, many of them civilians. The coalition, which includes Saudi Arabia's Gulf Arab allies, enjoys logistical backing from the United States but the White House condemned the bombing and said it was reviewing its assistance. Adding to the condemnation, Human Rights Watch said on Thursday that the air strike was "an apparent war crime" and "unlawfully disproportionate". The UK, a major seller of arms to Saudi Arabia, is to present a draft resolution to the UN Security Council next week calling for a ceasefire in Yemen.

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Volvo's parent company, Geely of China, bought the Swedish automaker six years ago from Ford and has spent around a billion dollars on Volvo to get it into fighting shape. One of the big things to come out of Volvo's turnaround was its new compact modular architecture, or CMA, which will be repurposed with Geely's new brand -- Lynk & Co. According to Automotive News and the Lynk & Co. website, the new brand will launch Oct. 20. While the website makes the new automaker look like an Urban Outfitters or Crate & Barrel competitor, it's supposed to be a mid-market Chinese domestic aimed at fighting successful American imports like Buick. Lynk & Co. is rumored to be launching with a sedan and an SUV, both of which will use Volvo’s CMA as their bones. With Lynk & Co. targeting the mid-market, Geely the brand competing with Chinese entry-level autos and Volvo fighting against premium nameplates, the Chinese automaker is trying to capitalize on every aspect of the market. Despite Geely giving every chance for Lynk & Co. to succeed, with China’s slowing car sales, this multi-million dollar push could become the modern Edsel. We won’t know for sure until cars start rolling out, but a slowing economy rarely spells success for a new car brand.

Young kids who miss daytime nap and also stay up late at night are likely to consume more calories, suggests new research. These findings may shed light on how sleep loss can increase weight gain and why a number of studies show that preschoolers who do not get enough sleep are more likely to be obese as a child and later in life. “To our knowledge, this is the first published study to experimentally measure the effects of sleep loss on food consumption in preschool children,” said study first author Elsa Mullins from University of Colorado Boulder in the US. “Our results are consistent with those from other studies of adults and adolescents, showing increased caloric intake on days that subjects were sleep deprived,” she said. In this small study, preschoolers were deprived of roughly three hours of sleep on one day – they had no afternoon nap and were kept up for about two hours past their normal bedtime – before being awakened at their regularly scheduled times the next morning During the day of lost sleep, the three- and four-year-olds consumed about 20 per cent more calories than usual, 25 per cent more sugar and 26 per cent more carbohydrates, lead study author Monique LeBourgeois, Assistant Professor at CU Boulder. The following day, the kids were allowed to sleep as much as they needed. On this “recovery day,” they returned to normal baseline levels of sugar and carbohydrate consumption, but still consumed 14 per cent more calories and 23 per cent more fat than normal. “We found that sleep loss increased the dietary intake of preschoolers on both the day of and the day after restricted sleep,” LeBourgeois said. The study was published in the Journal of Sleep Research.

Thousands of Thais have gathered at Bangkok's royal palace for late-night vigils to mourn King Bhumibol Adulyadej, who died on Thursday. His body was brought to the palace in a convoy as mourners lined the streets weeping. Millions watched live on TV. Crown Prince Maha Vajiralongkorn has been named as successor, but has asked for a delay in the process. A regent has been appointed. King Bhumibol was the world's longest-reigning monarch. Obituary: King Bhumibol What will the funeral be like? 'Gone, but not forgotten': Social media pays tribute How King Bhumibol shaped modern Thailand What do tourists need to know? He had been ill for a long time and died on Thursday. Official mourning will last a year. The cabinet declared Friday a government holiday, and flags are to fly at half-mast for the next 30 days. People have been asked to wear black, and avoid "joyful events" during this period. Cinema screenings, concerts and sports events have been cancelled or postponed. News websites have turned their pages black and white. All television channels in Thailand aired state media programmes including live coverage of the day's events. The country has suffered from political violence and upheaval over the past decade, as well as a long-running Muslim separatist insurgency in the southern provinces which sees regular small-scale bomb attacks. Though a constitutional monarch with limited official powers, many Thais looked to King Bhumibol to intervene in times of high tension. He was seen as a unifying and calming influence through numerous coups and 20 constitutions. However, his critics argued he had endorsed military takeovers and at times had failed to speak out against human rights abuses. Heir's challenge The crown prince, who is 64, is much less well known to Thais and has not attained his father's widespread po[CENSORED]rity. He spends much of his time overseas, often in Germany. While Prime Minister Prayuth Chan-ocha has said the crown prince will ascend the throne next, there is uncertainty over when that will happen. Mr Prayuth said the crown prince had asked for a delay in the succession as he wanted time to mourn with the nation. Profile: Crown Prince Vajiralongkorn

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Opening files and applications Each application on your computer has a group of file types—or formats—it is able to open. When you double-click a file, your computer will automatically use the correct application to open it. In our example, we're opening a Microsoft Word document (Chicago Trip Details), which will open in Microsoft Word. However, there may be times you may want to open an application directly, instead of just opening a file. To open an application in Windows, click the Start button, then select the desired application. If you don't see the one you want, you can click All Programs/All Apps to see a full list, or simply type the name of the application on your keyboard to search for it. In the example below, we're opening Internet Explorer. To open an application on a Mac, click the application's icon on the Dock. If you don't see the one you want, click the Spotlight icon in the top-right corner of the screen, then type the name of the application on your keyboard to search for it. In the example below, we're opening Safari. Adjusting your computer's settings When you start using a new computer, you may want to begin by adjusting the computer's settings. Adjusting your settings can range from simple tasks such as changing your desktop background to more advanced tasks like adjusting your security or keyboard settings. In Windows 10, click the Start button, then select Settings. In Windows 8.1 and earlier, click the Start button, then locate and select the Control Panel. Check out the Adjusting Your Settings lesson in our Windows Basics tutorial to learn more about the Control Panel. On a Mac, click the Apple icon, then select System Preferences. Check out our Adjusting Your Settings lesson in our OS X Basics tutorial to learn more about System Preferences. Shutting down your computer When you're done using your computer, it's important to shut it down properly. To shut down Windows, click the Start button, then select Shut down (in some versions, this may say Turn Off Computer or look like the power symbol). To shut down a Mac, click the Apple icon, then select Shut Down.

Google has zigged and zagged so often in its approach to hardware that it is hard to put too much stock in a branding change based on a single product launch. But Google’s move to kill off the Nexus brand in favor of Pixel has implications beyond the launch of a new phone. This is a lot bigger change than simply rebranding its screen-based hardware (so far, tablets, Chromebooks, and phones). It signals a major shift from a developer-enabling “proof of concept” line of phones under the Nexus brand to an attempt to compete head-to-head with flagships from Microsoft, Apple, and Samsung. Perhaps the closest analog to Google’s Pixel brand is Microsoft’s Surface. Originally floated as a statement of what was possible with Windows hardware, it has evolved into a key element of Microsoft’s devices and services strategy. Similarly, since the awkward consumer launch of the original Nexus One, Nexus has not been seriously promoted as a mass market product line by Google –although the phones’ attractive pricing and clean software made them po[CENSORED]r with plenty of non-developers. But now, Google’s Pixel and Pixel XL are clearly designed to compete directly with the Apple iPhone 7 and Samsung Galaxy 7 families of phones. This is reflected in the Pixel’s premium pricing. Unlike the Nexus phones, the Pixels are definitely not a bargain. Ranging in price from $650 to $870, they’re not going to be purchased based on low price. Google is on thinner ice with Pixel now The danger for Google as it tries to make Pixel a compelling value and a marketplace winner is that it will damage its Android ecosystem by giving itself, and its Pixels, what its partners perceive as unfair advantages. Google has already given the Pixel phones first crack at Android 7.1, and an exclusive on its much-touted Google Assistant for now. That’s in addition to the natural advantages it will have because Google is doing so much of the hardware design and the software — like the uniquely-powerful version of HDR+ in the camera, and gyroscopically coupled image stabilization (not unique to the Pixel, but tricky to pull off). Amazon has long since forked its version of Android, but now Samsung is becoming increasingly open about the possibility of using Tizen instead of Google’s Android on more of its devices. Samsung could probably only make that work by shipping a version of Tizen that runs most Android apps — but it wouldn’t be automatically tied into Google’s Play services and data collection framework. Pixel is also potential insurance on Google’s part against the possibility of Samsung moving away from Google’s version of Android, and no doubt a negotiating chip it can use with Samsung and others to help keep its ecosystem moving forward. Google may push things further by producing some of its own silicon for future versions of the Pixel.

When Intel bought Altera last year, there was speculation on how we’d see future FPGA products fit within Intel’s existing product lines. Intel has previously stated it intends to offer a Xeon processor with an integrated FPGA, but we’ve yet to hear any concrete talk about what that product will look like. The new Stratix 10 family does contain a microprocessor — but it’s an ARM-based design, not an Intel chip. That doesn’t mean Intel DNA isn’t baked into the new FPGA, however. According to Intel’s PR, Stratix 10 offers double the core performance, up to 70% lower power, up to 1TBps of memory bandwidth provided courtesy of HBM2 (that’s 128GB/s) and up to 10TFLOPS of single-precision floating point performance. ARM capabilities are provided by a quad-core Cortex-A53. According to Intel, Stratix 10 has been fundamentally re-architected to deliver performance that’s dramatically better than any competitive solution on the market. The new chip uses “hyper-registers” to reduce routing congestion and to allow for performance tuning without requiring additional adaptive logic modules (ALMs). The chip allows for localized programmable clock trees to reduce skew and timing uncertainty. This improvement was apparently “a key feature that allows the HyperFlex architecture to reach 2X performance.” Intel also points to new design tools and options that it claims allow the Stratix 10 to scale more effectively to deal with a variety of problems than other FPGAs. The chip is built on Intel’s 14nm Tri-Gate process. Altera isn’t Intel’s only foundry customer; Achronix has also built FPGAs with the Santa Clara company, but Achronix used Intel’s older 22nm process. FPGAs are a branch of computing we don’t typically discuss at ET. But they’ve been used extensively in data centers, software-defined networking, and device prototyping. The slide below broadly captures the difference between the three types of integrated circuits, and while it focuses on power efficiency, we can also take this as a broad stand-in for overall performance as well. At the far left-hand side of the graph, you have microprocessors like the general-purpose CPUs from AMD, Intel, and ARM. These chips all offer a great deal of flexibility — there’s a robust compiler ecosystem and a wide variety of tools for programming CPUs, and CPUs can any workload (albeit not necessarily very well). FPGAs are more energy efficient than CPUs, but not as flexible — they can be programmed to duplicate the functions and timings of other processors, which is why many of the replica consoles you can buy rely on FPGAs instead of relying on aging, original NES hardware. At the far end of the scale you have ASICs, which are built to do one particular task quite well and offer maximum performance, but limited reprogrammability. Modern GPUs are sometimes considered ASICs, though they have enough general-purpose compute functionality to argue the point (ASICs eventually took over cryptocurrency mining precisely because they could outperform GPUs).

Ken Block's 845-hp all-wheel-drive 1965 Ford Mustang coupe debuted at the 2014 SEMA Show and was slapped with the name Hoonicorn. Shortly after SEMA, Block dropped the seventh installment of his "Gymkhana" series, which featured the Hoonicorn ripping around Los Angeles and doing donuts underneath hopping lowriders. Currently, the video has over 38 million views on YouTube; the car is so po[CENSORED]r that it, along with Block, appeared on the latest season of the BBC show “Top Gear” tearing up the streets of England. With this year's SEMA show just around the corner, Block shed light on a new version of the Hoonicorn Mustang -- this time with two turbochargers feeding the methanol-drinking 6.7-liter Roush Yates Racing V8. With all the changes made ahead of the SEMA Show, the Hoonicorn now makes a ground-pounding 1,400 hp. The Hoonicorn V2 will naturally star in a “future video project” -- something that sounds a lot like the 10th "Gymkhana" video. After his hopes of shooting a video in Australia were dashed for "Gymkhana 9," we can’t even imagine where Block will film the next tire-slaying and internet-breaking video.

A strong network of friends may be just as big a factor in acts of group violence as having a charismatic leader or a savvy battle plan, according to a new study. The findings may also apply to potentially violent activities associated with terrorism, revolutions and gangs, researchers said. Researchers at Yale University in the US studied the social dynamics of the Nyangatom, a nomadic tribal group in East Africa that is regularly involved in violent raids with other groups. They mapped the interpersonal connections among Nyangatom men over a three-year period, focusing on how those friendship networks affected the initiation of raids and participation in those raids. “Social interactions in networks are crucial for the emergence of positive phenomena, like cooperation and innovation, but they also play a role in other sorts of collective behaviour, like the seemingly spontaneous emergence of violence,” said Nicholas Christakis, co-director of the Yale Institute for Network Science (YINS) and senior author of the study. “People go to war with their friends, and the social network properties of such violent activities have rarely been explored,” Christakis added. The study found that the initiation of Nyangatom raids depended on the presence of leaders who had participated in many raids, had more friends and held central positions in the social network. However, membership in raiding parties depended on a po[CENSORED]tion much larger than the leaders’ network of friends. Non-leaders, in fact, had a bigger impact on raid participation than leaders, by virtue of their own friendships. “Collective action doesn’t get off the ground with just a charismatic leader attracting random followers,” said Alexander Isakov, co-first author of the study and a postdoc at the Human Nature Lab at YINS. “People are driven to participate in the group predominantly due to friendship ties,” said Isakov. A surprising aspect of the findings, according to the researchers, was the interplay between leadership and friendship in an environment without any formal hierarchy. The Nyangatom raiding groups are informal groups of peers, yet individuals played distinct roles that mirrored a formal leadership structure. “They have no formal political leaders or chiefs,” said co-first author Luke Glowacki, a research fellow at the Institute for Advanced Study in France. “The lack of political centralisation creates an opportunity to study the social dynamics of collective action in a way that is difficult in a state society such as our own. We wanted to know how, outside of formal leadership or institutions, real-world collective behaviour, including violence, is initiated,” said Glowacki. The findings appear in the journal Proceedings of the National Academy of Sciences.

US singer Bob Dylan has been awarded the 2016 Nobel Prize for Literature, becoming the first songwriter to win the prestigious award. The 75-year-old rock legend received the prize "for having created new poetic expressions within the great American song tradition". The balladeer, artist and actor is the first American to win since novelist Toni Morrison in 1993. His songs include Blowin' in the Wind and The Times They are A-Changin'. Sara Danius, permanent secretary of the Swedish Academy, said Dylan had been chosen because he was "a great poet in the English speaking tradition". "For 54 years now he's been at it reinventing himself, constantly creating a new identity," she told reporters in Stockholm. The singer is due to perform later at the Cosmopolitan hotel in Las Vegas. 'Best words in best order' Dylan - who took his stage name from the poet Dylan Thomas - had long been tipped as a potential prize recipient. Few experts, though, expected the academy to extend the award to a genre such as folk rock music. Former Poet Laureate Sir Andrew Motion is among those to have previously praised Dylan's lyrics, saying his songs "work as poems". "They have often extremely skilful rhyming aspects to them," he told the BBC. "They're often the best words in the best order." Analysis by Colin Paterson, entertainment correspondent Bob Dylan - the first person to win a Nobel Prize the same day as he plays a gig in Las Vegas. What makes a man who has only ever written three books a suitable winner of the Nobel Prize for literature? Bob Dylan arguably made the lyrics more important than the music. Last Friday Dylan supported The Rolling Stones at the Desert Trip Festival in California and his set included Rainy Day Women #12 & 35 from that very album. It is a song with the refrain "everybody must get stoned," leading to decades-long debates about whether it deals with Old Testament-style punishment or a call to smoke cannabis. Or most probably both. Few would argue that is one of his finest lyrics, but it does demonstrate the mixture of political questioning, religious exploration and interest in humanity which has been woven through his work for more than 50 years and has secured him this award. The result also demonstrates a real change for the prize. In 112 years, no songwriter has ever won before. The decision elevates song lyrics to being on a critical par with literature, poetry and playwriting. It's a big step away from the self-perpetuating intellectualism and elitism for which the award had been criticised. Dylan was born Robert Allen Zimmerman in 1941 and began his musical career in 1959, playing in coffee houses in Minnesota. Much of his best-known work dates from the 1960s, when he became an informal historian of America's troubles. Blowin' in the Wind and The Times They are A-Changin' were among anthems of the anti-war and civil rights movements. His move away from traditional folk songwriting, paired with a controversial decision to "go electric" proved equally influential. Dylan's many albums include Highway 61 Revisited in 1965, Blonde on Blonde in 1966 and Blood on the Tracks in 1975. Since the late 1980s he has toured persistently, an undertaking he has dubbed the "Never-Ending Tour".

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Recall action affects 2016-17 Prius models Toyota will recall 92,000 2016-17 Prius hybrids in the U.S., 212,000 in Japan and 36,000 throughout the rest of the world, claiming “there is a possibility that the parking brake could become inoperative." Reportedly, the problem only occurs if a driver attempts to exit the Prius without first putting the transmission in park; in that case, where the emergency brake alone is used to hold the vehicle, there is a chance that the parking brake cable will fail. The repair is simple enough and will be free-of-cost to owners. Toyota plans on adding clips to the top of the brake cable dust boots, which will apparently help prevent the cable from failing. Toyota will let affected owners know in December, but you can always check your VIN against Toyota’s recall database. There are no official reports of accidents directly connected to the parking brake cable failure, but Toyota is looking into the matter. Just to be sure, if you happen to own one of the affected Prius models, you should double-check that you push the park button and power down the car before exiting.

Injecting a specific gene directly into the brain may offer a potential new therapy for halting the progress of Alzheimer’s disease, especially when treated at an early stage, a new study has claimed. Scientists from Imperial College London in the UK used a type of modified virus to deliver a gene to brain cells in mice. Previous studies by the same team suggest this gene, called PGC1 – alpha, may prevent the formation of a protein called amyloid-beta peptide in cells in the lab. Amyloid-beta peptide is the main component of amyloid plaques, the sticky clumps of protein found in the brains of people with Alzheimer’s disease. These plaques are thought to trigger the death of brain cells. Worldwide 47.5 million people are affected by dementia – of which Alzheimer’s is the most common form, researchers said. There is no cure, although current drugs can help treat the symptoms of the disease. Magdalena Sastre, senior author of the research, hopes the new findings may one day provide a method of preventing the disease, or halting it in the early stages. “Although these findings are very early they suggest this gene therapy may have potential therapeutic use for patients,” said Sastre. “There are many hurdles to overcome, and at the moment the only way to deliver the gene is via an injection directly into the brain. However this proof of concept study shows this approach warrants further investigation,” she said. The modified virus used in the experiments was called a lentivirus vector, and is commonly used in gene therapy, said Professor Nicholas Mazarakis, co-author of the study. In the new study, the team injected the virus, containing the gene PGC-1 – alpha, into two areas of the brain in mice susceptible to Alzheimer’s disease. The animals were treated at early stages of Alzheimer’s, when they still had not developed amyloid plaques. After four months, the team found that mice who received the gene had very few amyloid plaques, compared with the untreated mice, who had multiple plaques in their brain. The treated mice also performed as well in memory tasks as healthy mice. The tasks included challenges such as replacing a familiar object in the mouse’s cage with a new one. If the mice had a healthy memory, they would explore the new object for longer. The team also discovered there was no loss of brain cells in the hippocampus of the mice who received the gene treatment. The treated mice had a reduction in the number of glial cells, which in Alzheimer’s disease can release toxic inflammatory substances that cause further cell damage. The team suggests injections of the gene would be most beneficial in the early stages of the disease, when the first symptoms appear. The finding was published in the journal Proceedings of the National Academy of Sciences.

Singer Janet Jackson has officially confirmed she is expecting her first child, at the age of 50. She told People magazine: "We thank God for our blessing", and posed for a picture with her growing baby bump. Speculation about her pregnancy surfaced in April when she postponed her 'Unbreakable' tour, saying she wanted to focus on planning a family with her husband, Wissam al-Mana. She was recently spotted in London shopping for baby essentials. The People magazine quoted a source close to the Jackson family as saying: "She is super excited about her pregnancy and is doing extremely well. She actually feels very good about everything." In a video posted on Twitter in April, she told her fans that she was postponing her world tour because "there's been a sudden change". "I thought it was important that you be the first to know. My husband and I are planning our family," she said, adding: "Please if you can try and understand that its important that I do this now." She went on to say: "I have to rest up, doctor's orders." The 300-year-old fertility statistics still in use today Babies born to women aged 45 and over rise by a third Profile: Janet Jackson Janet Damita Jo Jackson was born on 16 May 1966 in Gary, Indiana in the US She is the youngest of nine children and sister of late pop icon Michael Jackson She released her first album Janet Jackson in 1982 She has a total of 11 albums with the most recent, Unbreakable, released in 2015 She is a seven-time Grammy award winner She began her career with the family's reality TV series The Jacksons in 1976 and has since appeared in several movies such as Tyler Perry's Why Did I Get Married The singer married her third husband, Qatari billionaire Wissam al-Mana, in 2012. Janet Jackson: The stories behind the songs Janet Jackson is far from the only famous face to give birth later in life. Oscar-winning Halle Berry had her second child at 47, three years ago, and John Travolta's wife Kelly Preston gave birth to her third child at 48. Geena Davis - best known for her role in Thelma and Louise - became a mother later in life after falling in love with an Iranian-American neurosurgeon in her 40s. Her first child, a girl, arrived when she was 46, followed two years later by twin boys. Then there was Swiss billionaire Maria Louis-Dreyfus, who gave birth to twin girls in March 2016, aged 53. But these mothers - and Jackson - are all positively young when compared to the world's oldest new mothers. In fact, there are at least three women in India who claimed to have carried their children to term when at least two decades older than the pop singer. Omkari Panwar, said to be 70, gave birth to twins, a boy and a girl, in 2008. A few months later, Rajo Devi Lohan - also 70 - gave birth to a little girl, her first, much-longed for child. Daljinder Kaur, who may be as old as 72, although she claimed to be just 70, gave birth to a son in April 2016 after three attempts at IVF. Each time, the births caused a debate over the ethical issues surrounding having a baby so late in life - especially after Maria del Carmen Bousada de Lara, the Spanish woman who once held the title of the world's oldest mother, died three years after having twin boys. All three are understood to have used donated eggs in order to have their children.

Sales decline gives the Camaro an edge, but even there it's all relative September wasn’t kind to the Ford Mustang: Sales plunged a whopping 32 percent last month, and in response, Ford has idled Mustang lines at its Flat Rock, Michigan, factory -- the only facility making the car -- for one week. According to Bloomberg, production will resume on Oct. 17. Workers will be paid in the interim. The report comes on the heels of news that Jeep saw sagging sales in September; the brand's single-digit overall decline may have been less startling, but the fact that can't-build-'em-fast-enough favorites like the Wrangler aren't flying off lots like they used to points to a broader trend. We can think of a few other reasons sales of enthusiast favorites like the rear-wheel-drive Mustang and convertible top-equipped Wrangler might be dipping this time of year (namely, the impending onset of winter and the arrival of 2017 model-year vehicles), but at this point a widespread cooling of the automotive market seems undeniable. It's not all dark clouds: Utilitarian vehicles like crossovers and trucks are still moving, at least for the time being. Plus, the massive miss in Mustang numbers also marks the first time the Chevrolet Camaro got a leg up in the pony-car sales battle since October 2014. Yet even there, we'll note that it's all relative, as both the Mustang and the Camaro are down year to date (9.3 and 11 percent each, respectively).

Some commonly prescribed blood pressure medications may increase the risk of mood disorders such as depression or bipolar disorder, researchers including one of Indian origin have warned. In the study, that compared four common classes of antihypertensive drugs and risk of mood disorders, two drugs were associated with an increased risk for mood disorders, while one appears to decrease mood disorder risk, according to Sandosh Padmanabhan, Professor at University of Glasgow in the UK. Researchers collected data on 525,046 patients (ages 40-80) from two large secondary care Scottish hospitals. They selected 144,066 patients being treated for hypertension with either angiotensin antagonists, beta blocker, calcium channel blockers or thiazide diuretics. They were compared to a group of 111,936 patients not taking any of those drugs. Researchers followed the patients for five years documenting hospitalisation for mood disorders, such as depression or bipolar disorder. After more than 90 days on the antihypertensive medications, they found that there were 299 hospital admissions, predominantly due to major depression, among the patients studied, at an average 2.3 years after patients began antihypertensive treatment. Patients on beta-blockers and calcium antagonists were at two-fold increased risk of hospital admission for mood disorder, compared to patients on angiotensin antagonists. Patients on angiotensin antagonists had the lowest risk for hospitalisation with mood disorders compared to patients on other blood pressure medicines and patients on no antihypertensive therapy. Those taking thiazide diuretics showed the same risk for mood disorders compared to patients taking no antihypertensive medicines. The presence of co-existing medical conditions increased the risk of mood disorders. These findings suggest that angiotensin-converting enzyme inhibitors and angiotensin-receptor blockers that are used to treat hypertension may be useful as new or “repurposed” treatments for mood disorders, according to Padmanabhan. The finding was published in the journal Hypertension.

An Upper Midwest flashback in the super-advanced descendent of the car of my childhood Every summer, I spend a week or two at a log cabin on Lake Michigan owned by my wife's family, on Wisconsin's Door County Peninsula. This area is about as pure a region as you'll find for love of Detroit vehicles, and you'll see levels of Buicks and Chryslers and Fords on the streets of Door County in numbers not seen on the coasts since the late 1970s. When I fly out to Wisconsin from my home in Denver, I must drive American during my visits; last year, I had a Ford Focus ST for this trip. That was a fine automobile, no complaints, but it wasn't the sort of machine that gave me a connection to the Detroit iron driven by my Midwestern forebears. I spent the first half-dozen years of my life in Minneapolis, and the first car I remember riding in was my mom's green 1949 Cadillac coupe. It was 20 years old and fairly rusty, but my parents called it Dillinger and, even as a 3-year-old, I knew it had style. My dad, meanwhile, drove a utilitarian 1967 Ford Custom 500 two-door post (the cheapest full-size Ford that year), with 289-cubic-inch V8 and three-on-the-floor manual transmission. These cars were very appropriate to a proper patriotic family in the Upper Midwest, but then the miserable Minnesota weather chased my family to the San Francisco Bay Area in 1972, making the move in a brand-new 1973 Chevrolet Sportvan Beauville passenger van. After that, my parents tried to stay loyal to Detroit cars, but a clanker of a 1979 Ford Granada and an even more wretched 1988 Chevrolet Celebrity pushed them into the eager embrace of Toyota and Mazda. My wife grew up in Milwaukee, a place very similar (culturally speaking) to Minneapolis. Her parents drove Buick Skylarks and Ford Country Squires, and her grandparents drove gigantic slab-sided Cadillacs. To this day, the keychain that holds the keys to the Door County log cabin comes from the Chicago-area dealership that sold Grandpa one of his Cadillacs. So, I needed a proper Cadillac for this trip. The Cadillac Division built some of the most technologically advanced and most prestigious cars in the world during a period lasting from about the end of World War II until the downward spiral that set in around the time of the 1973 OPEC oil embargo. Now Cadillac's engineering chops are back in full effect, and this car drives just as well as something built by those Germans. I didn't clip any apexes at 11/10ths nor did I explore the bleeding edge of the performance envelope in this car, mostly because the roads in Door County do not encourage such driving (and because most of the time my 76-year-old mother-in-law was in the car with me). However, I pushed it hard enough to recognize that the CTS AWD 2.0T is light-footed and extremely grippy, even to the point of sacrificing cushiness for the sake of handling -- something impossible to imagine the Cadillac Division of even 15 years ago being willing to do. With a very nervous small-displacement engine stuffed with serious boost in front and power to all four wheels, this car pulls hard with little turbocharger lag, the eight-speed automatic transmission downshifts without trying your patience and the whole package managed to get close to 25 miles per gallon with me doing mostly non-highway driving. My mother-in-law, upon hearing I would be driving a new Cadillac, expected the sort of standing-on-a-waterbed ride and acres-of-tufted-leather experience that one might get with an '84 Eldorado Biarritz. She drives a 10-year-old Accord and had a Supra before that, so she hadn't retained her Wisconsonian devotion to Detroit machinery … but the sportiness and firm ride of the CTS 2.0T disappointed her greatly. She felt it rode too harshly, made too much engine noise and shifted too frequently. However, when driving in town I noted many approving looks from locals, so the lesson here appears to be that those who remember both Cadillac's good years and bad years can find things to love and hate about this car \Me, I was impressed. I'd drive one of these things every day, although (because I'm old and an automotive journalist) I would much prefer a manual transmission. The Bose audio system may be the loudest factory-installed system I have experienced in any car, and I mean that in a positive, do-justice-to-bass-heavy-music sense; the interior is made entirely of nice stuff; and the highway range on a full tank should be a long-road-trip-encouraging 500-plus miles. And it's only a matter of time before the aftermarket sells a kit that lets you bolt on a bigger turbocharger and more, uh, flexible engine controls, for a hundred or two increased horsepower.

Drinking too much water may cause potentially fatal water intoxication, claims a new study which has for the first time identified the mechanism that regulates fluid intake in the human body and stops us from over-drinking. The study, led by researchers from Monash University in Australia, challenges the po[CENSORED]r idea that we should drink eight glasses of water a day for good health. It showed that a ‘swallowing inhibition’ is activated by the brain after excess liquid is consumed, helping maintain tightly calibrated volumes of water in the body. “If we just do what our body demands us to we will probably get it right – just drink according to thirst rather than an elaborate schedule,” said Michael Farrell, associate professor at Monash. The researchers asked participants to rate the amount of effort required to swallow water under two conditions; following exercise when they were thirsty and later after they were persuaded to drink an excess amount of water. The results showed a three-fold increase in effort after over-drinking. “Here for the first time we found effort-full swallowing after drinking excess water which meant they were having to overcome some sort of resistance. This was compatible with our notion that the swallowing reflex becomes inhibited once enough water has been drunk,” Farrell said. Researchers used functional magnetic resonance imaging (fMRI) to measure activity in various parts of the brain, focusing on the brief period just before swallowing. The fMRI showed the right prefrontal areas of the brain were much more active when participants were trying to swallow with much effort, suggesting the frontal cortex steps in to override the swallowing inhibition so drinking could occur according to the researcher’s instructions. “There have been cases when athletes in marathons were told to load up with water and died, in certain circumstances, because they slavishly followed these recommendations and drank far in excess of need,” he said. Drinking too much water in the body puts it in danger of water intoxication or hyponatremia, when vital levels of sodium in the blood become abnormally low potentially causing symptoms ranging from lethargy and nausea to convulsions and coma. Elderly people, however, often did not drink enough and should watch their intake of fluids, said Farrell. The study was published in the journal Proceedings of the National Academy of Sciences.

Voters in the US will vote on 8 November to decide who will be the country's next president. Use our poll tracker to follow the contest between the Democratic contender Hillary Clinton and her Republican rival Donald Trump. It will be a few days until the polls reflect any possible change in public opinion resulting from the second presidential debate. How important are national polls? It's a tough task to gauge the mood of a nation that is home to more than 300 million people, but that doesn't stop the pollsters from trying. National polls tend to have a sample size of about 1,000 people or more and can track movement and general opinion pretty well. But the US election is won and lost in swing states and decided by the electoral college system (What is the electoral college?). This means that polls in states that look like they could vote for either candidate (Florida, Ohio and Pennsylvania to name just a few) play an integral role in election projections. How does a US presidential election work? Are Trump and Clinton the only candidates? No. They're the only candidates that stand a real chance of winning the race, but there are other third-party and independent candidates in the running. The rules around getting on the ballot differ state to state, but most voters will have two main alternatives to Hillary Clinton and Donald Trump. Green Party candidate Jill Stein, 66, is a doctor and activist who is hoping to pick up Democrats who backed Bernie Sanders and continue to rally against Mrs Clinton. Former New Mexico governor Gary Johnson, 63, is standing for the Libertarian Party and focusing his efforts on attracting Republicans uneasy with Mr Trump. According to polling resource website RealClearPolitics, Mrs Stein is picking up about 2% of the vote in a four-way race while Mr Johnson is fairing slightly better at a little more than 7%. Neither can win the race with stats like that, but they could siphon enough voters off of the major candidates to change the outcome in a close race. Will third party candidates decide US election? How are Clinton's numbers looking? Hillary Clinton has long been the frontrunner in this contest but there have been times where she has looked far from comfortable. The most recent examples came back-to-back in early September. First, she made headlines by labelling half of Donald Trump's supporters a "basket of deplorables", allowing her rival to conclude it was evidence of her disdain for "hardworking people". Then just two days later, Mrs Clinton was filmed fainting after leaving a 9/11 memorial service early. It later emerged she had been suffering from pneumonia fuelling further rumours about her health - rumours that some of her critics have been pushing for months. Her poll numbers took a noticeable hit in the days that followed, but they appeared to recover towards the end of September. Will Clinton pay for her terrible weekend? When was Trump last ahead? The Republican candidate has made substantial gains on Mrs Clinton since her leads of about 20% in the summer of 2015 (when the field was far wider) but he has only crept ahead of her a few times. The last came after the Republican National Convention at the end of July when Mr Trump officially accepted the party's nomination. The lead didn't last long though, with his rival receiving a similar boost to her ratings at the end of the Democratic National Convention a few days later. What would a Donald Trump presidency look like? How did the VP picks affect the polls? In the past, an astute pick for a candidate's running mate could earn them a double-digit boost in the polls - Bill Clinton got a 12-point bounce after naming Al Gore as his pick for vice-president in 1992. But in recent years the bounces have been far smaller and 2016 followed that trend. Neither Trump's choice of Indiana Governor Mike Pence (15 July), or Clinton's unveiling of ex-Virginian governor Tim Kaine (22 July) changed much in the polls.

Wolfsburg slowly backs away from promises of new TDI models in the States Months after indicating diesel models may be back on sale in the U.S. in 2017, it appears Volkswagen will not offer diesel vehicles in the U.S. for the 2016 and 2017 model years. The automaker has not applied for certification of TDI vehicles from the VW, Audi and Porsche brands, weeks after several executives downplayed the chances of diesels making it back to the market in the near future. This gradual turn toward almost ruling out the return of TDI models to the American market took place over the last few months, with some pointing to VW's struggles in obtaining approval for a technical fix for affected U.S. models, as well as fears over customer response and dealer bottom line. "The future is electric," VW CEO Matthias Mueller said on the eve of the Paris auto show. "Nevertheless, classic powertrains will continue to play a key role for the next two decades, at least. We must and we will press ahead with the evolution of diesel and petrol engines. And at the same time, we will progress with alternative technologies." VW executives' hints regarding the issue only concern the U.S. and Canada; VW is not abandoning diesel in dozens of other world markets, including those where diesel sales are on par with gasoline-model sales. "'Diesel is and will remain an incisive turning point, a pivotal event in our history," Mueller added. "We are working with all available resources to get to the roots of this crisis and work our way through all of the issues. And we have made substantial progress in this regard in recent months. However, shaping a sustainable future for Volkswagen is at least as important." VW is still working on a technical solution for a portion of the 482,000 VW and Audi 2.0-liter TDI models expected to be repaired -- no greater than 15 percent of the remaining diesels on the road -- and an additional 85,000 VW, Audi and Porsche models that use the larger 3.0-liter engine. While VW reached a deal with U.S. federal authorities over the 2.0-liter diesel issue in June of this year, the fate of the larger diesels remains unresolved as VW works toward a solution that will be approved by the EPA -- expected to come sometime this month.

As summer transitions into winter, you ought to take good care of your skin while getting exposed to the sun and its rays. Give your skin more fluids and eat right for healthy skin, says an expert. October being the beginning of the festive season, is generally the time when most people plan their vacation. The days tend to be very hot and humid in October. So, Chandrika Mahendra, Principal Scientist, Personal Care, The Himalaya Drug Company, suggests how to keep skin glowing all day long. * One of the basic mantras for beating the October heat is to get more fluids into your body. Your skin glows and appears healthier when your body is adequately hydrated. If you are heading to one of the beaches in southern India, treat yourself generously with tender coconut water. It is not only low in calories but has anti-oxidants, Vitamin C and other essential minerals that enrich your skin. * Excessive oily food may cause acne, and the heat only makes it worse. Look for fruits that are rich in Vitamin C such as orange, lemon and kiwi. They help to maintain moisture balance in your skin and Vitamin C also helps build protection against skin wrinkling. *After a day-out in the sun, try out a natural anti-tan peel off mask. An orange-based peel off mask is a good pick. Oranges are rich in Vitamin C and the antioxidants present in the orange peel will work collectively to provide an even-textured skin and act as a natural cleanser. Ingredients such as honey can also act as an anti-bacterial element with healing properties.